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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP16
All Species:
17.58
Human Site:
S459
Identified Species:
38.67
UniProt:
Q9BY84
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BY84
NP_085143.1
665
73102
S459
S
E
Q
T
P
E
T
S
P
D
K
E
E
A
S
Chimpanzee
Pan troglodytes
XP_520751
665
73101
S459
S
E
Q
T
P
E
T
S
P
D
K
E
E
A
S
Rhesus Macaque
Macaca mulatta
XP_001084619
665
73124
S459
S
E
Q
T
P
E
T
S
P
D
K
E
E
A
S
Dog
Lupus familis
XP_543810
663
72657
S456
S
E
Q
T
P
E
T
S
P
D
K
E
E
A
N
Cat
Felis silvestris
Mouse
Mus musculus
O09112
663
68829
R458
C
R
P
R
P
R
R
R
R
P
P
A
S
S
P
Rat
Rattus norvegicus
NP_001100094
661
72804
P455
E
Q
T
P
E
T
S
P
D
K
E
E
A
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508628
481
51865
Y276
D
V
S
L
D
E
A
Y
R
F
V
K
E
K
R
Chicken
Gallus gallus
XP_428887
701
77250
P495
E
Q
T
P
E
A
S
P
D
K
E
E
A
N
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998405
539
59053
R334
L
S
G
V
S
E
E
R
L
L
A
R
A
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10038
657
70984
T452
A
E
L
P
S
P
S
T
E
L
S
R
L
S
F
Sea Urchin
Strong. purpuratus
XP_787378
916
99998
S662
S
P
P
P
I
Q
S
S
A
A
V
V
G
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.9
93
N.A.
44.2
90.5
N.A.
52.9
77.1
N.A.
54.5
N.A.
N.A.
N.A.
30.5
33.7
Protein Similarity:
100
99.5
99
95.7
N.A.
57.8
94.8
N.A.
60.5
83.4
N.A.
64.5
N.A.
N.A.
N.A.
46.1
47.6
P-Site Identity:
100
100
100
93.3
N.A.
6.6
6.6
N.A.
13.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
26.6
N.A.
20
26.6
N.A.
6.6
N.A.
N.A.
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
10
0
10
10
10
10
28
37
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
10
0
0
0
19
37
0
0
0
0
0
% D
% Glu:
19
46
0
0
19
55
10
0
10
0
19
55
46
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
19
37
10
0
10
0
% K
% Leu:
10
0
10
10
0
0
0
0
10
19
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
19
% N
% Pro:
0
10
19
37
46
10
0
19
37
10
10
0
0
0
19
% P
% Gln:
0
19
37
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
10
0
10
10
19
19
0
0
19
0
0
10
% R
% Ser:
46
10
10
0
19
0
37
46
0
0
10
0
10
19
28
% S
% Thr:
0
0
19
37
0
10
37
10
0
0
0
0
0
0
0
% T
% Val:
0
10
0
10
0
0
0
0
0
0
19
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _